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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7148fdf9c74d98dd805bdc835650ba78172a989f4946a6069900ad13d552d761' 
  AND token = 'wJbF3K9iCfXAiX1Cb7et1fGTIUBEQMXrjQ/KEqMCSr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}