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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6b77bc53ad223f77188ee60f14e9f1f96499e374321c3af9fb5066fbaf09c94' 
  AND token = 'Pg+VpdUO/3+ucoIo/CTNtFR25h72+aF0lW1V5Shpm0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}