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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81ffa75f97beb9934234e6663eb65d660dc52ac04dedcf73f57ac3245c5e5ae5' 
  AND token = '55bDHUSOtWPyu16T2lhdNUspBc65ZtvAgVWiF7J5Qeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}