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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ab5cfb4fd473a01c44b84cd6bd2b2df003cc2183ac396fe4fa21a05bb9f214a' 
  AND token = 'BOK7QYYBcikxFEkm7/VWV/8YBsf858Gw6eFoiuKx+g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}