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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44acd2951c3af636b72fa0c9ccc4c5d962a9919519b333b1231b074c6cf20228' 
  AND token = '87NMx5FwMctXghwjdI6XxMLrB8DC2jxiL0gs03EWvCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}