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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32297a01ec14e9ad57e122712ff08e0f48d9309e25ddc076cfe82006a9f33553' 
  AND token = 'lFVRVMxLoDS09uazST0Tb24ul7VFBrb20gxZIZ3xJr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}