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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d1dbed0d3e6e60397fd9ef2417749721a0c25f162d9e3674902773e684c0390' 
  AND token = 'uRFefx6r/fiEgHcILq32fvqH+W1wLkZc/JWqywwcIz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}