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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a473d46cd83e53ea8f4b4d66f20ac243140163d83d0d1f29f3921838d079280' 
  AND token = 'azOi9qALkFFw/nI6eN8rzE8Yx8/BqPZ2fUtFKEV3/44=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}