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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44166f29103596903fbac835985f0ad926685cd4547f398273be4a33aacbc83a' 
  AND token = '8ucX/XnwmeeSJxB459f4TkJz1s0IrxwAXoePisujxtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}