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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b8955050bdf7381bf05c0fa31e6084d58e0aa2210f51062d0a226cec5a7a3a2' 
  AND token = 'DL4c9ERitnZY4cRstTpOciyVL4YAOLefl+kcLTUOcpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}