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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb9d614f48ab27d9d6672795de92e8aad245d7f33ac43c672d72e4db411adeda' 
  AND token = 'fUPARvzSlb3fAQSbZQ0pgu2fWvevbPaHCuO4EkpuoiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}