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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8d049532a013af48d74feba967c5b5708cd7900a7fc7218370756be5bca9dac' 
  AND token = 'UN12DpSYEVmF/h5XbJGUpWOSf8BM2wkM7Ywfm0cchbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}