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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4308da90b4483d9c750ef40d1837fc076f40d7d08335c3ea752a46de1afd4dfe' 
  AND token = 'eAzKEA7zgI39HUXsW9+ssuakaSNNMYW42YPzgvAIKR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}