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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3e0273dcf0d5f882ed582887e0281f96d5d661b14b1263537b0e75b73827631' 
  AND token = 'zctKREUhP59IJ3l5vTMY3C3mr3x2tDwT1WdJyZRQdog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}