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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ddad3f0d1cb4b30d368c496772811f9d49aab695be5b92c0be8958a23733efce' 
  AND token = '5wVRsr6S9D4rWRL6uRS/gym2TA6HFhZT5Ro0j2oFyLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}