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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2d1bc008dbc48a14212e4474cac9f61bd6c88baf4261de8080a182819a1975a' 
  AND token = 'GxWHCrwlyG/sIZXMRR/XGxadeAxd/LuZvRnBpA3CSEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}