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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be22b9abe1a86afc760c6f8612eb6a48a6f2597c7b00bb66495341fb5116e79e' 
  AND token = 'PCFlgMgOX2FI+m/IHKQYfU3d0YXn6kL40qz69AddSjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}