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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '721dd0c9792fae019e6b7d37b7e32bfdaa71b157832a581b175003bded8abd3b' 
  AND token = 'dWolPOwfX49v13Du5HmULV3snUfPXQI5hIfCmbGVK1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}