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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458dca3f7efdf09e3cfe59146b6365ac9095c8feefe89eac9790995cf7b861fc' 
  AND token = 'gd6/vqT9p2M7+nB+uUBmsyw4Oh7N3U8i0PMZd7/WjLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}