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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e58274bb75118214901f723b6d57518afaf18e3dfc7bf904f4dc2b573955726' 
  AND token = 'DR3zfMv68HiMDjJ7zdnv47hyT60Hkre/P7F9bwrlM3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}