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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39c1bae0eee14bcf662e651ebba51be515c838010f6ff6b0cbb5284643def1e5' 
  AND token = 'TAVTM+z/0Jwb6YsJw9NWYQYO0pPKa1ZPO/7hICmG98g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}