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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8791138ecac98d30056e555737d2a5c5fff9bff807eb0fff59961e1b2234e8da' 
  AND token = 'hjlO/ZelN2mU6Zf21MDRnRkaO53APmN42jmgY1udPh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}