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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34bd5cc51c0e48325c512e901d7f487fee39b428f219d9d03f7a76f10c08ebf4' 
  AND token = 'eZ2urI7K3Gq1wTZkTCs+jv18dBuHoQ3Osl1ADymoSGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}