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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b18802f5169c3412cfd78bbb747f4bb73816243ae6a01b8fd8de84cc4263a1e' 
  AND token = 'G7qLo+R0o0z5nX41WPa/AlsA6g2ynB6OmvVIXuaHAeo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}