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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ece2563260e0cb40065bf58ffc78ad032316205bb52f98f2bc5bb0595e813463' 
  AND token = '3T1H8UETCMfBUgPcQT7dD0uvw7MHsZDNhvHtIFzBFW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}