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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c36ed125745669408fc43df4ff06bf4bd49747427619796fa7789b1635c6d08' 
  AND token = 'b3KSpWm3u3sE2R34dasmSa930vGTWLopO334KvrM8CI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}