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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b182203938e3a7db6d330b339a063016ef8f5006feab5695c04ae82b1a9940f8' 
  AND token = 'HTAx+mvdEsVEqTkNGl7sC4IHwNJj/NvswC+PPyI6X3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}