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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67969a29d056e25ddd294dc8fced4ac644d938ee2c1b4fa9082b70905742ccf5' 
  AND token = '7NXEr07gmb0DYufEVGHAY1tXFvQfPVzYUwk6Xuw2nFQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}