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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e7b00d7b4ec2754fbc677962eec51f0d91d9be5d47c5151883fc707cdf67ad1' 
  AND token = 'TVbnDXx3E5eK2vi+YRcAAzNKOeABfuncLca9dtEwFL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}