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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '153fd9ad3f5c98786305d05ce85c81f546547ffe5014bfba2cfc51e38dc6b8ee' 
  AND token = 'FisjyiP0hcuYRYxc2f628plzHXEcoF8dfhm+u82zSUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}