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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e43a92a84360b7c7f967dd44000d4d1a9f0b6b3704d33eb436e50649ff250f7' 
  AND token = 'u8WIqnEef4f0qmBBtfpm53JHzwgVw0i0+d4bvPchxZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}