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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '792e2d4de437f57d96680192746ea34a82224899de6551bb6d136b884e80a833' 
  AND token = 'U5Crj/Fye6D81VbQTayr8a8OeCZLiCLmhiOLP05H97U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}