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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de34287a004e1224dc82ae02e68489ce380ed681e44599a8ae25791a298a3d0e' 
  AND token = 'KdymlmeDDN01Ud+Wpp4roI3CjTsQylD2FSyNs8UJUt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}