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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3912569cad2fd06985ae427baeed1032b52866c453020da4e2a8eace7c891da' 
  AND token = 's8sZiUpIs76a8Y/Utf+4IXYNKvvo7fHe8h6/jahAdVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}