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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fc04341f1786be3eeea7e853d5efbbaf62cd9046d2b89aff0a973fb21c9dec0' 
  AND token = 'd15txSVmDsu7DTh3g+eB1VtdwEX89ALY2XzqxklIX5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}