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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '274228da14e61fc4b4265d5023976818a70b75c4b71dbb2b1d2f2418f30c2c8c' 
  AND token = 'mS9uypea6cmFVyuAE9ZAxWbcIKcYjQMydyS1rl/bq/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}