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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77b5b25dadaa26e4ec8bb5c8f86b876182727ab474c8447c3951d0ce27ea8db5' 
  AND token = 'UWwpABgrmCCH6pXZ+nOUk+W8cezcJirunD+q1bW24Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}