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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb41246cc36b349db1ec31f3f839b1167d6077c90dd905b7d03536d0859765a5' 
  AND token = 'rL74ddBAqI8PrvpxtWmmrqa/YyL/MQfKVGqr9bHxifA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}