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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00146b655a723a26b420e91a16bdb0633c075619bcae741c0bad3dd26e7d43c3' 
  AND token = 'xd7UMswuxrKBp2sZ1LUsVPcMDCSWq/w7FZaiwIL5134=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}