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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1114acdd173ae668263869ebbee4e7b372f71afcbe56d1f1fa31127f5afdf42a' 
  AND token = '+3IVRY9oaSFZ1gUem78GluMbwOFaD17kEx0todF03ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}