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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2e016b73ffc49fdbe5495180ba9ac9ef511007d5390c9ae40aa1f46eedf9b3' 
  AND token = '++2BwFhS+KxsxK0mfUQtIiH7R62HLTB40PN1KGO2Lw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}