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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '105bd54d8f551afa18d22133ced7b856b9804240e95eec04fb8042d1c024b641' 
  AND token = 'PnSAtkMfX1tlEk9jK1b1P1Q8JtdnpszfCt+XBVOB+Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}