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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b274f2136765130a7f82835cf5ad1f7bb67986b8a710fdf8d95a1dec68f5307' 
  AND token = 'IVm/0EL9yjoPDxjG0LV+7iOcI3XhyLPWkHhWpcTSutM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}