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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45555787d6307bf97aa5bed3e16a2a5a0a7e379c03fb35f6c8722e231f23fefb' 
  AND token = 'MhBDfbB+iIf8+sQP1pi5DqMt2bQyW+w4svq2CovRF1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}