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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '159e9d1ce0b69ffc0efd532013db9b435cf99f83c66ee9efc7f63137fa4c4af7' 
  AND token = '9q9qmj5SYNPY2P9UD2cxXNtWgv6ivuvCxIvBZo954Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}