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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd383a0f15c9056c14cbc05700b6fb7a1b3500c478e30ceab38b245c034013f46' 
  AND token = 'RqNMPCmy4cuXtDlaG0sbz5EaU0L2eTIKfXjKE5EjaP0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}