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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea25758fca410d8c4a1cffb27bd9080d884cc240edaf033930eaf8110e8c8a5' 
  AND token = '7bKOj0wueztqM94qf0DxtQLpfqjUwdxEuaj01v+U0As=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}