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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416f207419877a0ff05a04f834cff31c497daf82bb0beae0c8a2f5afab00c979' 
  AND token = 'yzHOsCB0+9i4tUzdbaP/Tcs/IpzcBZI3lqgmpFnqPEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}