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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '55d4d20ae8a0ed10699844fe0f1b03c881a1598088eb3d118f064c98b667327c' 
  AND token = '2+L6Uv3mmQnjrmF6yj9y6YOsPybj0jGxvuoDbKrcsTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}