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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd53ae57c9b4fdfc5cab1ab1cc17e62c9d2b65c80e403d4290e80d65fbe1893bf' 
  AND token = 'P7Yu2tLvD7ZjGHh1bfBOAzX8tatgNPqo18xvHis9MPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}